Eligible commercially insured patients who are prescribed ENSPRYNG for an FDA-approved use can receive up to $20,000 in assistance per 12-month period.

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Indication and Important Safety Information

ENSPRYNG Important Safety Information

What is ENSPRYNG?
ENSPRYNG is a prescription medicine used to treat neuromyelitis optica spectrum disorder (NMOSD) in adults who are aquaporin-4 (AQP4) antibody positive. It is not known if ENSPRYNG is safe and effective in children.

Who should not receive ENSPRYNG?
Do not take ENSPRYNG if you:

  • are allergic to ENSPRYNG or any of the ingredients in ENSPRYNG.
  • have an active hepatitis B infection.
  • have active or untreated inactive (latent) tuberculosis.

What is the most important information I should know about ENSPRYNG?
ENSPRYNG may cause serious side effects including:

  • Infections: ENSPRYNG can increase your risk of serious infections some of which can be life-threatening. Talk to your healthcare provider if you have or think you have an infection.
    • Your healthcare provider should test you for hepatitis and tuberculosis (TB) before you start taking ENSPRYNG.
    • All required vaccinations should be completed before starting ENSPRYNG.
  • Increased liver enzymes: Your healthcare provider should order blood tests to check your liver enzymes before and while you are taking ENSPRYNG.
  • Low neutrophil count: ENSPRYNG can cause a decrease in your neutrophil counts in your blood. Neutrophils are white blood cells that help the body fight off bacterial infections.
  • Serious allergic reactions: Serious allergic reactions that may be life-threatening have happened with other medicines like ENSPRYNG.

What are the most common side effects of ENSPRYNG?
The most common side effects of ENSPRYNG include:

  • sore throat, runny nose (nasopharyngitis)
  • rash
  • fatigue
  • extremity pain
  • headache
  • upper respiratory tract infection
  • nausea
  • inflammation of the stomach lining (gastritis)
  • joint pain (arthralgia)

These are not all the possible side effects of ENSPRYNG.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to Genentech at 1-888-835-2555.

For more information, go to www.ENSPRYNG.com or call 1-844-NSPRYNG.

For additional safety information, please see the full Prescribing Information and Medication Guide.